DR1 Antibody (Down-regulator of transcription 1) | F45943-0.08ML

DR1 Antibody (Down-regulator of transcription 1) | F45943-0.08ML | Gentaur US, UK & Europe Disrtribition

Family: Primary antibody

Formulation: In 1X PBS, pH 7.4, with 0.09% sodium azide

Format: Antigen affinity purified

Clone: N/A

Host Animal: Rabbit

Clonality: Polyclonal (rabbit origin)

Species Reactivity: Human, Mouse

Application: WB, ELISA

Buffer: N/A

Limitation: This DR1 antibody is available for research use only.

Purity: Antigen affinity

Description: This gene encodes a TBP- (TATA box-binding protein) associated phosphoprotein that represses both basal and activated levels of transcription. The encoded protein is phosphorylated in vivo and this phosphorylation affects its interaction with TBP. This protein contains a histone fold motif at the amino terminus, a TBP-binding domain, and a glutamine- and alanine-rich region. The binding of DR1 repressor complexes to TBP-promoter complexes may establish a mechanism in which an altered DNA conformation, together with the formation of higher order complexes, inhibits the assembly of the preinitiation complex and controls the rate of RNA polymerase II transcription.

Immunogen: A portion of amino acids 83-112 from the human protein was used as the immunogen for this DR1 antibody.

Storage: Aliquot the DR1 antibody and store frozen at -20 °C or colder. Avoid repeated freeze-thaw cycles.