Description
Doublecortin Antibody / DBCN / DCX | RQ4745 | Gentaur US, UK & Europe Disrtribition
Family: Primary antibody
Formulation: Antibody in PBS with 0.02% sodium azide and 50% glycerol
Format: Purified
Clone: AOAD-4
Host Animal: Rabbit
Clonality: Rabbit Monoclonal
Species Reactivity: Human, Rat
Application: WB
Buffer: N/A
Limitation: This Doublecortin antibody is available for research use only.
Purity: Affinity purified
Description: The neuronal migration protein Doublecortin is a microtubule-associated protein required for initial steps of neuronal dispersion and cortex lamination during cerebral cortex development. May act by competing with the putative neuronal protein kinase DCLK1 in binding to a target protein. May in that way participate in a signaling pathway that is crucial for neuronal interaction before and during migration, possibly as part of a calcium ion-dependent signal transduction pathway. May be part with PAFAH1B1/LIS-1 of overlapping, but distinct, signaling pathways that promote neuronal migration. [UniProt]
Immunogen: A synthetic peptide specific to human Doublecortin / DCX was used as the immunogen for the Doublecortin antibody.
Storage: Store the Doublecortin antibody at -20 °C.