DOK5 Polyclonal Antibody | E-AB-64809

DOK5 Polyclonal Antibody | E-AB-64809 | Gentaur US, UK & Europe Disrtribition

Reactivity: Mouse, Rat

Host: Rabbit

Isotype: IgG

Application: WB

Research Area: Signal Transduction

Background: The protein encoded by this gene is a member of the DOK family of membrane proteins, which are adapter proteins involved in signal transduction. The encoded protein interacts with phosphorylated receptor tyrosine kinases to mediate neurite outgrowth and activation of the MAP kinase pathway. Unlike other DOK family proteins, this protein does not interact with RASGAP. This protein is up-regulated in patients with systemic sclerosis and is associated with fibrosis induced by insulin-like growth factor binding protein 5. Alternative splicing of this gene results in multiple transcript variants.

Lead Time: 7~10 days

Concentration: 1 mg/mL

Storage: Store at -20°C. Avoid freeze / thaw cycles.

Immunogen: Recombinant fusion protein of human DOK5 (NP_060901.2).

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3

Purification: Affinity purification

Dilution: WB 1:500-1:2000

Conjugation: Unconjugated

Calculated Molecular Weight: 22 kDa/35 kDa

Observed Molecular Weight: 30 kDa

Clonality: N/A