Dnmt3b Antibody | F40611-0.4ML

Dnmt3b Antibody | F40611-0.4ML | Gentaur US, UK & Europe Disrtribition

Family: Primary antibody

Formulation: In 1X PBS, pH 7.4, with 0.09% sodium azide

Format: Purified

Clone: N/A

Host Animal: Rabbit

Clonality: Polyclonal (rabbit origin)

Species Reactivity: Human

Application: WB, IHC, ELISA

Buffer: N/A

Limitation: This Dnmt3b antibody is available for research use only.

Purity: Purified

Description: CpG methylation is an epigenetic modification that is important for embryonic development, imprinting, and X-chromosome inactivation. Studies in mice have demonstrated that DNA methylation is required for mammalian development. Dnmt3b is a DNA methyltransferase which is thought to function in de novo methylation, rather than maintenance methylation. The protein localizes primarily to the nucleus and its expression is developmentally regulated. Mutations in this gene cause the immunodeficiency-centromeric instability-facial anomalies (ICF)syndrome.

Immunogen: A portion of amino acids 389-417 from the human protein was used as the immunogen for this Dnmt3b antibody.

Storage: Aliquot the Dnmt3b antibody and store frozen at -20 °C or colder. Avoid repeated freeze-thaw cycles.