Description
Dnmt3a Antibody | F40604-0.4ML | Gentaur US, UK & Europe Disrtribition
Family: Primary antibody
Formulation: In 1X PBS, pH 7.4, with 0.09% sodium azide
Format: Antigen affinity purified
Clone: N/A
Host Animal: Rabbit
Clonality: Polyclonal (rabbit origin)
Species Reactivity: Human
Application: WB, IHC, ELISA
Buffer: N/A
Limitation: This Dnmt3a antibody is available for research use only.
Purity: Antigen affinity
Description: CpG methylation is an epigenetic modification that is important for embryonic development, imprinting, and X-chromosome inactivation. Studies in mice have demonstrated that DNA methylation is required for mammalian development. Dnmt3a is a DNA methyltransferase that is thought to function in de novo methylation, rather than maintenance methylation. The protein localizes to the cytoplasm and nucleus and its expression is developmentally regulated. [Wiki]
Immunogen: A portion of amino acids 457-486 from the human protein was used as the immunogen for this Dnmt3a antibody.
Storage: Aliquot the Dnmt3a antibody and store frozen at -20 °C or colder. Avoid repeated freeze-thaw cycles.