Description
Dnmt1 Antibody | V7716SAF-100UG | Gentaur US, UK & Europe Disrtribition
Family: Primary antibody
Formulation: 1 mg/ml in 1X PBS; BSA free, sodium azide free
Format: Purified
Clone: DNMT1/2061
Host Animal: Mouse
Clonality: Monoclonal (mouse origin)
Species Reactivity: Human
Application: IHC-P
Buffer: N/A
Limitation: This DNMT1 antibody is available for research use only.
Purity: Protein G affinity chromatography
Description: This gene encodes an enzyme that transfers methyl groups to cytosine nucleotides of genomic DNA. This protein is the major enzyme responsible for maintaining methylation patterns following DNA replication and shows a preference for hemi-methylated DNA. Methylation of DNA is an important component of mammalian epigenetic gene regulation. Aberrant methylation patterns are found in human tumors and associated with developmental abnormalities. Variation in this gene has been associated with cerebellar ataxia, deafness, and narcolepsy, and neuropathy, hereditary sensory, type IE.
Immunogen: Amino acids 767-912 from the human protein was used as the immunogen for the DNMT1 antibody.
Storage: Store the DNMT1 antibody at 2-8oC (with azide) or aliquot and store at -20 °C or colder (without azide).
