DJ-1 Antibody | F49626-0.08ML

DJ-1 Antibody | F49626-0.08ML | Gentaur US, UK & Europe Disrtribition

Family: Primary antibody

Formulation: In 1X PBS, pH 7.4, with 0.09% sodium azide

Format: Purified

Clone: N/A

Host Animal: Rabbit

Clonality: Polyclonal (rabbit origin)

Species Reactivity: Human, Mouse

Application: WB, IF, ELISA

Buffer: N/A

Limitation: This DJ-1 antibody is available for research use only.

Purity: Purified

Description: Park7/DJ-1 acts as positive regulator of androgen receptor-dependent transcription, and may function as redox-sensitive chaperone and as sensor for oxidative stress, as well as preventing aggregation of SNCA. This protein has been shown to protect neurons against oxidative stress and cell death, and to play a role in fertilization. It is detected in tau inclusions in brains from neurodegenerative disease patients, and is generally highly expressed in pancreas, kidney, skeletal muscle, liver, testis and heart, with detectable levels in placenta, brain, astrocytes, Sertoli cells, spermatogonia, spermatids and spermatozoa. Defects in Park7/DJ-1 are the cause of autosomal recessive early-onset Parkinson disease 7, a form of Parkinson disease characterized by onset before 40 years, slow progression and initial good response to levodopa.

Immunogen: A portion of amino acids 1-30 from the human protein was used as the immunogen for this DJ-1 antibody.

Storage: Aliquot the DJ-1 antibody and store frozen at -20 °C or colder. Avoid repeated freeze-thaw cycles.