Desmoglein 2 Antibody / DSG2 | RQ5646

Desmoglein 2 Antibody / DSG2 | RQ5646 | Gentaur US, UK & Europe Disrtribition

Family: Primary antibody

Formulation: 0.5mg/ml if reconstituted with 0.2ml sterile DI water

Format: Antigen affinity purified

Clone: N/A

Host Animal: Rabbit

Clonality: Polyclonal

Species Reactivity: Human

Application: WB, IHC-P, IF, FACS, Direct ELISA

Buffer: Lyophilized from 1X PBS with 2% Trehalose and 0.025% sodium azide

Limitation: This Desmoglein 2 antibody is available for research use only.

Purity: Affinity purified

Description: Desmoglein-2 is a protein that in humans is encoded by the DSG2 gene. These desmoglein gene family members are located in a cluster on chromosome 18. This second family member is expressed in colon, colon carcinoma, and other simple and stratified epithelial-derived cell lines. Mutations in DSG2 display a high degree of penetrance. Disease expression was of variable severity with LV involvement a prominent feature. The low prevalence of classical ECG changes highlights the need to expand current diagnostic criteria to take account of LV disease, childhood disease expression, and incomplete penetrance.

Immunogen: Recombinant human protein (amino acids L24-E1020) was used as the immunogen for the Desmoglein 2 antibody.

Storage: After reconstitution, the Desmoglein 2 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20 °C. Avoid repeated freezing and thawing.