Description
Desmin Antibody | R30031 | Gentaur US, UK & Europe Disrtribition
Family: Primary antibody
Formulation: 0.5mg/ml with 1% BSA and 0.01% sodium azide if reconstituted with 0.2ml sterile 1XPBS
Format: Ascites
Clone: DE-U-10
Host Animal: Mouse
Clonality: Monoclonal (mouse origin)
Species Reactivity: Human, mouse, rat, rabbit
Application: WB, IHC-P
Buffer: N/A
Limitation: This Desmin antibody is available for research use only.
Purity: Unpurified ascites
Description: Desmin belongs to the type III family of intermediate filaments, a class of cytoskeletal elements. The DES gene encodes a cytoskeletal protein found in smooth, cardiac, and heart muscles. Tidball(1992) found that Desmin was codistributed with actin thin filaments within the cellular processes of myotendinous junctions in frog skeletal muscle. DES gene contains 9 exons and spans about 8.4 kb. By in situ hybridization, Viegas-Pequignot et al.(1989) localized the gene to 2q35. Mutations are responsible for idiopathic dilated cardiomyopathy.
Immunogen: Desmin from pig stomach was used as the immunogen for this Desmin antibody.
Storage: After reconstitution, the Desmin antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20 °C. Avoid repeated freezing and thawing.
