DENND1B Polyclonal Antibody | E-AB-18656

DENND1B Polyclonal Antibody | E-AB-18656 | Gentaur US, UK & Europe Disrtribition

Reactivity: Human, Mouse

Host: Rabbit

Isotype: IgG

Application: WB, ELISA

Research Area: Cell Biology

Background: Clathrin (see MIM 118955)-mediated endocytosis is a major mechanism for internalization of proteins and lipids. Members of the connecdenn family, such as DENND1B, function as guanine nucleotide exchange factors (GEFs) for the early endosomal small GTPase RAB35 (MIM 604199) and bind to clathrin and clathrin adaptor protein-2 (AP2; see MIM 601024). Thus, connecdenns link RAB35 activation with the clathrin machinery.

Lead Time: 7~10 days

Concentration: 0.54 mg/mL

Storage: Store at -20°C. Avoid freeze / thaw cycles.

Immunogen: Fusion protein of human DENND1B

Buffer: PBS with 0.05% NaN3 and 40% Glycerol, pH7.4

Purification: Antigen affinity purification

Dilution: WB 1:500-1:2000, ELISA 1:5000-1:10000

Conjugation: Unconjugated

Calculated Molecular Weight: 86 kDa

Observed Molecular Weight: Refer to figures

Clonality: Polyclonal