DENND1B Antibody | F54541-0.08ML

DENND1B Antibody | F54541-0.08ML | Gentaur US, UK & Europe Disrtribition

Family: Primary antibody

Formulation: In 1X PBS, pH 7.4, with 0.09% sodium azide

Format: Purified

Clone: N/A

Host Animal: Rabbit

Clonality: Polyclonal (rabbit origin)

Species Reactivity: Human

Application: FACS, IHC-P, WB

Buffer: N/A

Limitation: This DENND1B antibody is available for research use only.

Purity: Antigen affinity purified

Description: Clathrin-mediated endocytosis is a major mechanism for internalization of proteins and lipids. Members of the connecdenn family, such as DENND1B, function as guanine nucleotide exchange factors (GEFs) for the early endosomal small GTPase RAB35 and bind to clathrin and clathrin adaptor protein-2. Thus, connecdenns link RAB35 activation with the clathrin machinery.

Immunogen: A portion of amino acids 39-68 from the human protein was used as the immunogen for the DENND1B antibody.

Storage: Aliquot the DENND1B antibody and store frozen at -20 °C or colder. Avoid repeated freeze-thaw cycles.