Description
Den1, GST-tag | 81084 | Gentaur US, UK & Europe Disrtribition
Category: Ubiquitination/Deubiquitylating Enzymes
Application: This enzyme is active in the NEDD8-IsoPro assay. Suggested Substrate: NEDD8-AMC
Background: DEN1 (SENP8, NEDP1) is a deNEDDylase that deconjugates NEDD8 conjugates. A recent study demonstrated that DEN1 deNEDDylated the tumor suppressor breast cancer-associated protein BCA3. Full length DEN1 cleaves NEDD8-PLA2 with high efficiency.
Description: Human Den1 recombinant protein, with GST-tag, expressed in E. coli.
Product Type: Protein
Shippement Condition: -80°C (dry ice)