Description
DEFA1 Polyclonal Antibody | E-AB-12365 | Gentaur US, UK & Europe Disrtribition
Reactivity: Human
Host: Rabbit
Isotype: IgG
Application: WB, ELISA
Research Area: Immunology, Microbiology
Background: Defensins are a family of microbicidal and cytotoxic peptides thought to be involved in host defense. They are abundant in the granules of neutrophils and also found in the epithelia of mucosal surfaces such as those of the intestine, respiratory tract, urinary tract, and vagina. Members of the defensin family are highly similar in protein sequence and distinguished by a conserved cysteine motif. The protein encoded by this gene, defensin, alpha 1, is found in the microbicidal granules of neutrophils and likely plays a role in phagocyte-mediated host defense. Several alpha defensin genes are clustered on chromosome 8. This gene differs from defensin, alpha 3 by only one amino acid. This gene and the gene encoding defensin, alpha 3 are both subject to copy number variation.
Lead Time: 7~10 days
Concentration: 0.4 mg/mL
Storage: Store at -20°C. Avoid freeze / thaw cycles.
Immunogen: Synthetic peptide of human DEFA1
Buffer: PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Purification: Affinity purification
Dilution: WB 1:500-1:1000
Conjugation: Unconjugated
Calculated Molecular Weight: 10 kDa
Observed Molecular Weight: N/A
Clonality: Polyclonal