DCX Antibody | F48191-0.4ML

DCX Antibody | F48191-0.4ML | Gentaur US, UK & Europe Disrtribition

Family: Primary antibody

Formulation: In 1X PBS, pH 7.4, with 0.09% sodium azide

Format: Antigen affinity purified

Clone: N/A

Host Animal: Rabbit

Clonality: Polyclonal (rabbit origin)

Species Reactivity: Human

Application: IHC, WB, ELISA

Buffer: N/A

Limitation: This DCX antibody is available for research use only.

Purity: Antigen affinity

Description: In the developing cortex, cortical neurons must migrate over long distances to reach the site of their final differentiation. DCX is a cytoplasmic protein which appears to direct neuronal migration by regulating the organization and stability of microtubules. It contains two doublecortin domains, which bind microtubules. In addition, this protein interacts with LIS1, the regulatory gamma subunit of platelet activating factor acetylhydrolase, and this interaction is important to proper microtubule function in the developing cortex. Mutations in the gene encoding DCX are a cause of X-linked lissencephaly.

Immunogen: A portion of amino acids 107-137 from the human protein was used as the immunogen for this DCX antibody.

Storage: Aliquot the DCX antibody and store frozen at -20 °C or colder. Avoid repeated freeze-thaw cycles.