Description
DAT - CHOK1 Recombinant Cell Line | 60558 | Gentaur US, UK & Europe Disrtribition
Category: Cell Line/Membrane Transporter
Application: • Monitor dopamine uptake activity • Screen for activators or inhibitors of DAT activities in a cellular context
Background: The dopamine transporter (DAT, SLC6A3) is a membrane-spanning protein that pumps the neurotransmitter dopamine out of the synaptic cleft back into the cytosol, from which other transporters sequester DA and norepinephrine (NE) into vesicles for storage and later release. Dopamine reuptake via DAT provides the primary mechanism through which dopamine is cleared from synapses. DAT is implicated in a number of dopamine-related disorders, including attention deficit hyperactivity disorder, bipolar disorder, clinical depression, and alcoholism.
Description: Recombinant CHOK1 cell line expressing Human sodium-dependent dopamine transporter (DAT), Genbank accession number NM_001044
Product Type: Cell Line
Shippement Condition: -80°C
