Description
Cytokeratin 8 /18 Antibody | V3113IHC-7ML | Gentaur US, UK & Europe Disrtribition
Family: Primary antibody
Formulation: Prediluted in 1X PBS with 0.1 mg/ml BSA (US sourced) and 0.05% sodium azide; *For IHC use only*
Format: Purified
Clone: SPM141
Host Animal: Mouse
Clonality: Monoclonal (mouse origin)
Species Reactivity: Human
Application: IHC-P
Buffer: N/A
Limitation: This Cytokeratin 8/18 antibody is available for research use only.
Purity: Protein G affinity chromatography
Description: Cytokeratin 8 (CK8) belongs to the type II (or B or basic) subfamily of high molecular weight cytokeratins and exists in combination with cytokeratin 18 (CK18). This mAb recognizes all simple epithelia including glandular epithelium, for example thyroid, female breast, gastrointestinal tract, respiratory tract, and urogenital tract including transitional epithelium. All adenocarcinomas and most squamous carcinomas are positive but keratinizing squamous carcinomas are usually negative. This antibody is useful in demonstrating the presence of Paget cells; there is very little keratin 18 in the normal epidermis so only Paget cells are stained.
Immunogen: A Keratin preparation from human breast carcinoma MCF-7 cells was used as the immunogen for the Cytokeratin 8/18 antibody.
Storage: Store the Cytokeratin 8/18 antibody at 2-8oC (with azide) or aliquot and store at -20 °C or colder (without azide).
