Description
Cytokeratin 5/6 Antibody | V8493-20UG | Gentaur US, UK & Europe Disrtribition
Family: Primary antibody
Formulation: 0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced), 0.05% sodium azide
Format: Purified
Clone: KRT5.6/2438
Host Animal: Mouse
Clonality: Monoclonal (mouse origin)
Species Reactivity: Human
Application: IHC-P
Buffer: N/A
Limitation: This Cytokeratin 5/6 antibody is available for research use only.
Purity: Protein G affinity chromatography
Description: It recognizes polypeptides of 58kDa and 56kDa, identified as cytokeratin 5 and 6 respectively. It shows no reaction with keratin 1, 8, or 19. It stains the basal cells of squamous and glandular epithelia, part of stratum spinosum of squamous epithelium, myoepithelium, and mesothelium. It does not stain adenous epithelium. Therefore, this antibody can be used to distinguish squamous carcinoma from adenocarcinoma, and to differentiate epitheliod mesothelioma from non-epitheliod mesothelioma and adenocarcinoma. It is also a useful antibody in the identification of mesothelioma and lung squamous cell carcinoma.
Immunogen: Recombinant full-length human KRT5 protein was used as the immunogen for the Cytokeratin 5/6 antibody.
Storage: Store the Cytokeratin 5/6 antibody at 2-8oC (with azide) or aliquot and store at -20 °C or colder (without azide).