Cytokeratin 20 Antibody / CK20 | V9328-20UG

Cytokeratin 20 Antibody / CK20 | V9328-20UG | Gentaur US, UK & Europe Disrtribition

Family: Primary antibody

Formulation: 0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced), 0.05% sodium azide

Format: Purified

Clone: KRT20/4879R

Host: Rabbit

Clonality: Recombinant Rabbit Monoclonal

Isotype: Rabbit IgG, kappa

Species Reactivity: Human

Application: IHC-P

Application Details: Immunohistochemistry (FFPE): 2-4ug/ml

Application Note: Optimal dilution of the recombinant Keratin 20 antibody should be determined by the researcher.

Purity: Protein A/G affinity

Description: This MAb recognizes an intermediate filament protein of 46kDa, identified as cytokeratin 20 (KRT20). KRT20 is abundantly expressed in goblet cells and enterocytes of the gastrointestinal tract. It is a useful marker of pancreatic and colorectal cancer. KRT20 is expressed under normal, hyperplastic and neoplastic conditions. It has been detected in adenocarcinomas of the colon, stomach and biliary tract. Breast carcinomas are generally non-reactive.

Immunogen: A portion of amino acids 196-323 was used as the immunogen for the recombinant Keratin 20 antibody.

Storage: Aliquot the recombinant Keratin 20 antibody and store frozen at -20 °C or colder. Avoid repeated freeze-thaw cycles.

Localization: Cytoplasmic