Cytokeratin 13 Antibody / KRT13 | V7916-100UG

Cytokeratin 13 Antibody / KRT13 | V7916-100UG | Gentaur US, UK & Europe Disrtribition

Family: Primary antibody

Formulation: 0.2 mg/ml with 0.1 mg/ml BSA (US sourced), 0.05% sodium azide

Format: Purified

Clone: KRT13/2659

Host Animal: Mouse

Clonality: Monoclonal (mouse origin)

Species Reactivity: Human

Application: IF, IHC-P

Buffer: N/A

Limitation: This Cytokeratin 13 antibody is available for research use only.

Purity: Protein G affinity chromatography

Description: Cytokeratin 13 (KRT13) is the major acidic keratin, which together with KRT4, its basic partner, is expressed in the suprabasal layers of non-cornified stratified epithelia including tongue mucosa, esophagus, anal canal epithelium, tracheal epithelium, uterine cervix, and urothelium. Defects in the KRT13 gene are a cause of white sponge nevus of cannon (WSN), a rare autosomal dominant disorder, which predominantly affects non-cornified stratified squamous epithelia and is characterized by the presence of soft, white and spongy plaques in the oral mucosa. KRT13 has been used as a marker for non-keratinized squamous epithelium. It is also expressed in various squamous metaplasia, but it is down regulated in squamous dysplasia and squamous carcinoma.

Immunogen: A recombinant full-length human KRT13 protein was used as the immunogen for this Cytokeratin 13 antibody.

Storage: Store the Cytokeratin 13 antibody at 2-8oC (with azide) or aliquot and store at -20 °C or colder (without azide).