Description
Cytokeratin 1 Antibody | V7908-20UG | Gentaur US, UK & Europe Disrtribition
Family: Primary antibody
Formulation: 0.2 mg/ml with 0.1 mg/ml BSA (US sourced), 0.05% sodium azide
Format: Purified
Clone: KRT1/1840
Host Animal: Mouse
Clonality: Monoclonal (mouse origin)
Species Reactivity: Human, Rat
Application: IHC-P
Buffer: N/A
Limitation: This CK1 antibody is available for research use only.
Purity: Protein G affinity chromatography
Description: Keratins are a family of intermediate filament proteins that assemble into filaments through forming heterodimers of one type I keratin (keratins 9 to 23) and one type II keratin (keratins 1 to 8). Keratins demonstrate tissue and differentiation specific expression profiles. Cytokeratin 1 is a hetero-tetramer of two type I as well as two type II keratins, keratin-10 (KRT10). Keratin 1 is differentiation specific keratin that is one of the predominant keratins in suprabasal keratinocytes in stratified epithelia. Mutations in keratin 1 cause epidermolytic hyperkeratosis.
Immunogen: A recombinant full-length human Cytokeratin 1 protein was used as the immunogen for this CK1 antibody.
Storage: Store the CK1 antibody at 2-8oC (with azide) or aliquot and store at -20 °C or colder (without azide).
