Cytochrome p450 2C19 Antibody / CYP2C19 | F54877-0.4ML

Cytochrome p450 2C19 Antibody / CYP2C19 | F54877-0.4ML | Gentaur US, UK & Europe Disrtribition

Family: Primary antibody

Formulation: In 1X PBS, pH 7.4, with 0.09% sodium azide

Format: Purified

Clone: N/A

Host Animal: Rabbit

Clonality: Polyclonal (rabbit origin)

Species Reactivity: Human

Application: IF, WB, IHC-P

Buffer: N/A

Limitation: This Cytochrome p450 2C19 antibody is available for research use only.

Purity: Purified

Description: CYP2C19 is a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum and is known to metabolize many xenobiotics, including the anticonvulsive drug mephenytoin, omeprazole, diazepam and some barbiturates. Polymorphism within its gene is associated with variable ability to metabolize mephenytoin, known as the poor metabolizer and extensive metabolizer phenotypes.

Immunogen: A portion of amino acids 82-108 from the human protein was used as the immunogen for the Cytochrome p450 2C19 antibody.

Storage: Aliquot the Cytochrome p450 2C19 antibody and store frozen at -20 °C or colder. Avoid repeated freeze-thaw cycles.