Description
CYP3A4 Antibody | RQ5252 | Gentaur US, UK & Europe Disrtribition
Family: Primary antibody
Formulation: Antibody in PBS with 0.02% sodium azide and 50% glycerol
Format: Purified
Clone: ACDE-3
Host Animal: Rabbit
Clonality: Rabbit Monoclonal
Species Reactivity: Human
Application: WB
Buffer: N/A
Limitation: This CYP3A4 antibody is available for research use only.
Purity: Affinity purified
Description: Cytochromes P450 are a group of heme-thiolate monooxygenases. In liver microsomes, this enzyme is involved in an NADPH-dependent electron transport pathway. It performs a variety of oxidation reactions (e.g. caffeine 8-oxidation, omeprazole sulphoxidation, midazolam 1'-hydroxylation and midazolam 4-hydroxylation) of structurally unrelated compounds, including steroids, fatty acids, and xenobiotics. The enzyme also hydroxylates etoposide.
Immunogen: A synthetic peptide specific to human Cytochrome P450 3A4 / CYP3A4 was used as the immunogen for the CYP3A4 antibody.
Storage: Store the CYP3A4 antibody at -20 °C.
