CYP2E1 Antibody | F51257-0.4ML

CYP2E1 Antibody | F51257-0.4ML | Gentaur US, UK & Europe Disrtribition

Family: Primary antibody

Formulation: In 1X PBS, pH 7.4, with 0.09% sodium azide

Format: Purified

Clone: N/A

Host Animal: Rabbit

Clonality: Polyclonal (rabbit origin)

Species Reactivity: Human

Application: WB, IHC, FACS, ELISA

Buffer: N/A

Limitation: This CYP2E1 antibody is available for research use only.

Purity: Purified

Description: CYP2E1 is a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum and is induced by ethanol, the diabetic state, and starvation. The enzyme metabolizes both endogenous substrates, such as ethanol, acetone, and acetal, as well as exogenous substrates including benzene, carbon tetrachloride, ethylene glycol, and nitrosamines which are premutagens found in cigarette smoke. Due to its many substrates, this enzyme may be involved in such varied processes as gluconeogenesis, hepatic cirrhosis, diabetes, and cancer.

Immunogen: A portion of amino acids 402-429 from the human protein was used as the immunogen for this CYP2E1 antibody.

Storage: Aliquot the CYP2E1 antibody and store frozen at -20 °C or colder. Avoid repeated freeze-thaw cycles.