Description
CYP2D6 Antibody | R36473-100UG | Gentaur US, UK & Europe Disrtribition
Family: Primary antibody
Formulation: 0.5 mg/ml in 1X TBS, pH7.3, with 0.5% BSA (US sourced) and 0.02% sodium azide
Format: Antigen affinity purified
Clone: N/A
Host Animal: Goat
Clonality: Polyclonal (goat origin)
Species Reactivity: Human
Application: WB, ELISA (peptide)
Buffer: N/A
Limitation: This CYP2D6 antibody is available for research use only.
Purity: Antigen affinity
Description: CYP2D6, a member of the cytochrome P450 mixed-function oxidase system, is one of the most important enzymes involved in the metabolism of xenobiotics in the body. In particular, CYP2D6 is responsible for the metabolism and elimination of approximately 25% of clinically used drugs, via the addition or removal of certain functional groups – specifically, hydroxylation, demethylation, and dealkylation – at various points along a substrate's core structure. This enzyme also metabolizes several endogenous substances, such as hydroxytryptamines, neurosteroids, and both m-tyramine and p-tyramine which CYP2D6 metabolizes into dopamine in the brain and liver. [Wiki]
Immunogen: Amino acids PTGQPRPSHH were used as the immunogen for this CYP2D6 antibody.
Storage: Aliquot and store the CYP2D6 antibody at -20 °C.
