Description
CYP21A2 Antibody / Steroid 21-hydroxylase | F54956-0.08ML | Gentaur US, UK & Europe Disrtribition
Family: Primary antibody
Formulation: In 1X PBS, pH 7.4, with 0.09% sodium azide
Format: Purified
Clone: N/A
Host Animal: Rabbit
Clonality: Polyclonal (rabbit origin)
Species Reactivity: Human
Application: WB, IF, IHC-P, FACS
Buffer: N/A
Limitation: This Steroid 21-hydroxylase antibody is available for research use only.
Purity: Purified
Description: CYP21A2 is a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum and hydroxylates steroids at the 21 position. Its activity is required for the synthesis of steroid hormones including cortisol and aldosterone. Mutations in CYP21A2 gene cause congenital adrenal hyperplasia.
Immunogen: A portion of amino acids 216-246 from the human protein was used as the immunogen for the Steroid 21-hydroxylase antibody.
Storage: Aliquot the Steroid 21-hydroxylase antibody and store frozen at -20 °C or colder. Avoid repeated freeze-thaw cycles.
