CYP1A1 / CYP1A2 Antibody | V7709SAF-100UG

CYP1A1 / CYP1A2 Antibody | V7709SAF-100UG | Gentaur US, UK & Europe Disrtribition

Family: Primary antibody

Formulation: 1 mg/ml in 1X PBS; BSA free, sodium azide free

Format: Purified

Clone: MC1

Host Animal: Mouse

Clonality: Monoclonal (mouse origin)

Species Reactivity: Human, Mouse, Rat

Application: IF, WB, IHC-P

Buffer: N/A

Limitation: This CYP1A1/1A2 antibody is available for research use only.

Purity: Protein G affinity chromatography

Description: Cytochrome P450 oxidase (commonly abbreviated CYP) is a generic term for a large number of related, but distinct, oxidative enzymes important in vertebrate physiology. The cytochrome P450 mixed-function monooxygenase system is probably the most important element of Phase I metabolism in mammals. P450s are membrane-bound, either in the inner membrane of mitochondria or in the endoplasmic reticulum of cells where they metabolise thousands of endogenous and exogenous compounds. In the liver, these substrates include toxins, drugs, and other unneeded and potentially harmful molecules. Humans have 18 families of cytochrome P450 genes and 43 subfamilies; the CYP1 family is involved in drug metabolism and includes 3 subfamilies, 3 genes and 1 pseudogene.

Immunogen: 3-methylcholanthrene induced rat cytochrome P450 protein was used as the immunogen for the CYP1A1/1A2 antibody.

Storage: Store the CYP1A1/1A2 antibody at 2-8oC (with azide) or aliquot and store at -20 °C or colder (without azide).