Cynomolgus Siglec-10 Protein, His Tag (MALS verified) | SI0-C52H5-1mg

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SKU:
716-SI0-C52H5-1mg
Availability:
IN STOCK
Weight:
1.20 KGS
€3,184.00
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Description

Cynomolgus Siglec-10 Protein, His Tag (MALS verified) | SI0-C52H5-1mg| Gentaur Distribution US, UK & Europe

The siglecs (sialic acid-binding Ig-like lectins) are a distinct subset of the Ig superfamily with adhesion-molecule-like structure. We describe here a novel member of the siglec protein family that shares a similar structure including five Ig-like domains, a transmembrane domain, and a cytoplasmic tail containing two ITIM-signaling motifs. Siglec-10 was identified through database mining of an asthmatic eosinophil EST library. The Siglec-10-VAP-1 interaction seems to mediate lymphocyte adhesion to endothelium and has the potential to modify the inflammatory microenvironment via the enzymatic end products.

Source: Cynomolgus Siglec-10, His Tag (SI0-C52H5) is expressed from human 293 cells (HEK293). It contains AA Thr 17 - Ala 549 (Accession # A0A2K5WBX8-1).

Format: Powder.

Tag: C-10×His.

Expression System: HEK293.

Expression Region: Thr 17 - Ala 549.

Conjugate: Unconjugated.

Molecular Weight: 60.2 kDa.

Characteristics: This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 60.2 kDa. The protein migrates as 65-75 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.

Purity: 95%.

Buffer: 25 mM MES, 150 mM NaCl, 0.5 M Arginine, pH5.0.

Storage Conditions: -20℃.

Shipping Conditions: RT

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Additional Information

Size:
1 mg
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