Description
Cynomolgus/Rhesus macaque IL-31 RA Protein, Fc Tag | ILA-H525b-100ug| Gentaur Distribution US, UK & Europe
Interleukin-31 receptor subunit alpha is a protein that in humans is encoded by the IL31RA gene, also known as IL-31 receptor subunit alpha, IL-31RA, GLM-R, Gp130-like receptor, CRL3, GPL. Oncostatin M receptor (OSMR) and IL31RA form the heterodimeric receptor through which IL31 signals. IL31RA is a strong activator of STAT3 and STAT5, whereas STAT1 is only marginally tyrosine-phosphorylated. dditionally, demonstrate Jak1 binding to GPL and its activation in heteromeric complexes with the OSMRbeta but also in a homomeric receptor complex.
Source: Cynomolgus/Rhesus macaque IL-31 RA Protein, Fc Tag (ILA-H525b) is expressed from human 293 cells (HEK293). It contains AA Ala 20 - Glu 519 (Accession # XP_005556977.2).
Format: Powder.
Tag: C-Fc.
Expression System: HEK293.
Expression Region: Ala 20 - Glu 519.
Conjugate: Unconjugated.
Molecular Weight: 84.5 kDa.
Characteristics: This protein carries a human IgG1 Fc tag at the C-terminus. The protein has a calculated MW of 84.5 kDa. The protein migrates as 110-140 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
Purity: 90%.
Buffer: PBS, pH7.4.
Storage Conditions: -20℃.
Shipping Conditions: RT
