Description
Cynomolgus / Rhesus macaque CD27 / TNFRSF7 Protein, Mouse IgG2a Fc Tag, low endotoxin | CD7-C5259-100ug| Gentaur Distribution US, UK & Europe
CD Antigen CD27 is also known as Tumor necrosis factor receptor superfamily member 7 (TNFRSF7), which belongs to TNF-receptor superfamily. CD27 / TNFRSF7 is found in most T-lymphocytes. CD27 / TNFRSF7 is required for generation and long-term maintenance of T cell immunity. It binds to ligand CD70, and plays a key role in regulating B-cell activation and immunoglobulin synthesis. This receptor transduces signals that lead to the activation of NF-κB and MAPK8/JNK. CD27 has been shown to interact with SIVA1, TRAF2 and TRAF3.
Source: Cynomolgus / Rhesus macaque CD27 Protein, Mouse IgG2a Fc Tag (CD7-C5259) is expressed from human 293 cells (HEK293). It contains AA Ala 20 - Arg 191 (Accession # XP_005569963.1). In the region Ala 20 - Arg 191, the AA sequence of Cynomolgus and Rhesus macaque CD27 are homologus.
Format: Powder.
Tag: C-mFc (mIgG2a).
Expression System: HEK293.
Expression Region: Ala 20 - Arg 191.
Conjugate: Unconjugated.
Molecular Weight: 46.2 kDa.
Characteristics: This protein carries a mouse IgG2a Fc tag at the C-terminus. The protein has a calculated MW of 46.2 kDa. The protein migrates as 50-66 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
Purity: 95%.
Buffer: 50 mM Tris, 100 mM Glycine, pH7.5.
Storage Conditions: -20℃.
Shipping Conditions: RT
