Cynomolgus PADI2 Protein, His Tag (MALS verified) | PA2-C5545-1mg

Cynomolgus PADI2 Protein, His Tag (MALS verified) | PA2-C5545-1mg| Gentaur Distribution US, UK & Europe

Protein-arginine deiminase type-2 (PADI2) are calcium-dependent histone-modifying enzymes whose activity is dysregulated in inflammatory diseases and cancer. This enzyme which catalyze the post-translational deimination of proteins by converting arginine residues into citrullines in the presence of calcium ions. The type II enzyme is the most widely expressed family member. Known substrates for this enzyme include myelin basic protein in the central nervous system and vimentin in skeletal muscle and macrophages.

Source: Cynomolgus PADI2, His Tag (PA2-C5545) is expressed from Baculovirus-Insect cells. It contains AA Met 1 - Pro 665 (Accession # A0A2K5TST4-1).

Format: Liquid.

Tag: N-10×His.

Expression System: InsectCells.

Expression Region: Met 1 - Pro 665.

Conjugate: Unconjugated.

Molecular Weight: 77.6 kDa.

Characteristics: This protein carries a polyhistidine tag at the N-terminus. The protein has a calculated MW of 77.6 kDa. The protein migrates as 66-70 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.

Purity: 95%.

Buffer: PBS, 1 mM EDTA, 0.5 mM TCEP, pH7.4.

Storage Conditions: -70℃.

Shipping Conditions: Dry ice