Description
Cynomolgus NKG2C / CD159c Protein, His Tag | NKC-C5247-1mg| Gentaur Distribution US, UK & Europe
Human NKG2C (NK cell Group 2 isoform C; Killer cell lectin-like receptor subfamily C, member 2) is a member of the C-type lectin-like superfamily of proteins. NKG2C plays a role as a receptor for the recognition of MHC class I HLA-E molecules by NK cells and some cytotoxic T-cells. The CD94/NKG2C killer lectin-like receptor (KLR) specific for HLA-E is coupled to the KARAP/DAP12 adapter in a subset of NK cells, triggering their effector functions. CD94/NKG2C may operate as an alternative activation pathway for a subset of CD8+ T lymphocytes, triggering their effector functions and proliferation upon specific ligand engagement.
Source: Cynomolgus NKG2C, His Tag (NKC-C5247) is expressed from human 293 cells (HEK293). It contains AA Ile 94 - Leu 231 (Accession # Q68VD0-1).
Format: Powder.
Tag: N-10×His.
Expression System: HEK293.
Expression Region: Ile 94 - Leu 231.
Conjugate: Unconjugated.
Molecular Weight: 17.8 kDa.
Characteristics: This protein carries a polyhistidine tag at the N-terminus. The protein has a calculated MW of 17.8 kDa. The protein migrates as 25 kDa, 27-30 kDa and 35-110 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
Purity: 85%.
Buffer: PBS, pH7.4.
Storage Conditions: -20℃.
Shipping Conditions: RT
