Description
Cynomolgus MICA Protein, His Tag (HPLC verified) | MIA-C52H5-100ug| Gentaur Distribution US, UK & Europe
MHC class I polypeptide-related sequence A (MICA) belongs to the MHC class I family and MIC subfamily. MICA contains one Ig-like C1-type (immunoglobulin-like) domain. Unlike classical MHC class I molecules, MICA does not form a heterodimer with beta-2-microglobulin. MICA acts as a stress-induced self-antigen that is recognized by gamma delta T-cells. MICA is ligand for the KLRK1/NKG2D receptor. MICA bind to KLRK1 leads to cell lysis.
Source: Cynomolgus MICA Protein, His Tag (MIA-C52H5) is expressed from human 293 cells (HEK293). It contains AA Leu 25 - Trp 304 (Accession # A0A7N9D4J5).
Format: Powder.
Tag: C-10×His.
Expression System: HEK293.
Expression Region: Leu 25 - Trp 304.
Conjugate: Unconjugated.
Molecular Weight: 33.9 kDa.
Characteristics: This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 33.9 kDa. The protein migrates as 48-60 kDa when calibrated against Star Ribbon Pre-stained Protein Marker under reducing (R) condition (SDS-PAGE) due to glycosylation.
Purity: 90%.
Buffer: PBS, pH7.4.
Storage Conditions: -20℃.
Shipping Conditions: RT