Description
Cynomolgus Integrin alpha V beta 3 (ITGAV&ITGB3) Heterodimer Protein, His Tag&Tag Free | IT3-C52W3-1mg| Gentaur Distribution US, UK & Europe
Integrin alpha-V/beta-3 (ITGAV:ITGB3) is a receptor for cytotactin, fibronectin, laminin, matrix metalloproteinase-2, osteopontin, osteomodulin, prothrombin, thrombospondin, vitronectin and von Willebrand factor. Integrins alpha-IIb/beta-3 and alpha-V/beta-3 recognize the sequence R-G-D in a wide array of ligands. Also, Integrin alpha-V/beta-3 acts as a receptor for herpes virus 8/HHV-8, coxsackievirus A9, Hantaan virus, cytomegalovirus/HHV-5, human metapneumovirus, human parechovirus 1 and west nile virus. Furthermore, in case of HIV-1 infection, the interaction with extracellular viral Tat protein seems to enhance angiogenesis in Kaposi's sarcoma lesions.
Source: Cynomolgus Integrin alpha V beta 3 (ITGAV&ITGB3) Heterodimer Protein, His Tag&Tag Free (IT3-C52W3) is expressed from human 293 cells (HEK293). It contains AA Phe 31 - Pro 993 & Gly 27 - Asp 718 (Accession # A0A2K5WCD3-1 & A0A2K5WYN9).
Format: Powder.
Tag: C-10×His | Native.
Expression System: HEK293.
Expression Region: Phe 31 - Pro 993 & Gly 27 - Asp 718.
Conjugate: Unconjugated.
Molecular Weight: 113 kDa & 81.7kDa.
Characteristics: Cynomolgus Integrin alpha V beta 3 (ITGAV&ITGB3) Heterodimer Protein, His Tag&Tag Free, produced by co-expression of ITGAV and ITGB3, has a calculated MW of 113 kDa (ITGAV) and 81.7 kDa (ITGB3). The protein migrates as 90 kDa and 150 kDa when calibrated against Star Ribbon Pre-stained Protein Marker under non-reducing (NR) condition (SDS-PAGE) due to glycosylation.
Purity: 90%.
Buffer: 50 mM Tris, 150 mM NaCl, pH8.0.
Storage Conditions: -20℃.
Shipping Conditions: RT
