Cynomolgus CX3CL1 / Fractalkine Protein, His Tag (MALS verified) | CX1-C5222-1mg

Cynomolgus CX3CL1 / Fractalkine Protein, His Tag (MALS verified) | CX1-C5222-1mg| Gentaur Distribution US, UK & Europe

Fractalkine is also known as C-X3-C motif chemokine 1 (CX3CL1) and neurotactin. Fractalkine is a large cytokine protein of 373 amino acids, it contains multiple domains and is the only known member of the CX3C chemokine family. Fractalkine is found commonly throughout the brain, particularly in neural cells, and its receptor is known to be present on microglial cells. It has also been found to be essential for microglial cell migration. CX3CL1 is also up-regulated in the hippocampus during a brief temporal window following spatial learning, the purpose of which may be to regulate glutamate-mediated neurotransmission tone. This indicates a possible role for the chemokine in the protective plasticity process of synaptic scaling.

Source: Cynomolgus CX3CL1 Protein, His Tag (CX1-C5222) is expressed from human 293 cells (HEK293). It contains AA Gly 24 - Ala 352 (Accession # A0A872TN34-1).

Format: Powder.

Tag: C-10×His.

Expression System: HEK293.

Expression Region: Gly 24 - Ala 352.

Conjugate: Unconjugated.

Molecular Weight: 36.5 kDa.

Characteristics: This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 36.5 kDa. The protein migrates as 50-75 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.

Purity: 90%.

Buffer: PBS, pH7.4.

Storage Conditions: -20℃.

Shipping Conditions: RT