Description
Cynomolgus CA125 / MUC16 Protein, His Tag (MALS verified) | CA5-C52H8-100ug| Gentaur Distribution US, UK & Europe
The CA125, also known as the MUC16, is a mucin protein that may be found in type I transmembrane or secreted forms that are used monitor the progress of epithelial ovarian cancer therapy. The CA 125 molecule is almost certainly a glycoprotein with a predominance of O-linkages. It is heterogeneous with regard to both size and charge, most likely due to continuous deglycosylation of side chains during its life-span in bodily fluids. It exists as a very large complex (perhaps as much as 4 million daltons) under natural conditions.
Source: Cynomolgus CA125 Protein, His Tag (CA5-C52H8) is expressed from human 293 cells (HEK293). It contains AA Pro 11544 - Pro 12188 (Accession # XP_045234963.1).
Format: Powder.
Tag: C-10×His.
Expression System: HEK293.
Expression Region: Pro 11544 - Pro 12188.
Conjugate: Unconjugated.
Molecular Weight: 73.9 kDa.
Characteristics: This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 73.9 kDa. The protein migrates as 95-120 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
Purity: 90%.
Buffer: PBS, pH7.4.
Storage Conditions: -20℃.
Shipping Conditions: RT