Description
Cynomolgus B7-H3 / CD276 Protein, His Tag (MALS verified) | B73-C52Ha-1mg| Gentaur Distribution US, UK & Europe
B7 homolog 3 (B7-H3), a member of the immunoglobulin superfamily, is also known CD276, which contains two Ig-like C2-type (immunoglobulin-like) domains and two Ig-like V-type (immunoglobulin-like) domains. B7-H3 may participate in the regulation of T-cell-mediated immune response. B7-H3 also plays a protective role in tumor cells by inhibiting natural-killer mediated cell lysis as well as a role of marker for detection of neuroblastoma cells. Furthermore, B7-H3 is involved in the development of acute and chronic transplant rejection and in the regulation of lymphocytic activity at mucosal surfaces. It could also play a key role in providing the placenta and fetus with a suitable immunological environment throughout pregnancy.
Source: Cynomolgus B7-H3, His Tag (B73-C52Ha) is expressed from human 293 cells (HEK293). It contains AA Leu 29 - Glu 465 (Accession # XP_015308534.1).
Format: Powder.
Tag: C-10×His.
Expression System: HEK293.
Expression Region: Leu 29 - Glu 465.
Conjugate: Unconjugated.
Molecular Weight: 49.0 kDa.
Characteristics: This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 49.0 kDa. The protein migrates as 60-70 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
Purity: 95%.
Buffer: PBS, pH7.4.
Storage Conditions: -20℃.
Shipping Conditions: RT
