Description
Cynomolgus APRIL / TNFSF13 Protein, His, Flag Tag, active trimer (MALS verified) | APL-C52D2-100ug| Gentaur Distribution US, UK & Europe
APRIL (a proliferation-inducing ligand) is also known as Tumor necrosis factor ligand superfamily member 13, TALL-2, TRDL-1, CD256, TNFFSF 13, cytokine that binds to TNFRSF13B/TACI and to TNFRSF17/BCMA. APRIL is a cytokine of the tumor necrosis factor family associated mainly with hematologic malignancies. The closely related TNF family ligands B cell activation factor (BAFF) and a proliferation-inducing ligand (APRIL) serve in the generation and maintenance of mature B-lymphocytes. Both BAFF and APRIL assemble as homotrimers that bind and activate several receptors that they partially share. BAFF-APRIL heteromers of different stoichiometries have distinct receptor-binding properties and activities. In addition, expression of APRIL was regulated by miR-145 in GC cells.
Source: Cynomolgus APRIL, His, Flag Tag (APL-C52D2) is expressed from human 293 cells (HEK293). It contains AA Gln 111 - Leu 250 (Accession # XP_005582818.1) trimer Design.
Format: Powder.
Tag: N-10×His & N-Flag.
Expression System: HEK293.
Expression Region: Gln 111 - Leu 250.
Conjugate: Unconjugated.
Molecular Weight: 50.4 kDa.
Characteristics: This protein carries a polyhistidine tag at the N-terminus, followed by a flag tag. The protein has a calculated MW of 50.4 kDa. The protein migrates as 55-65 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
Purity: 95%.
Buffer: PBS, pH7.4.
Storage Conditions: -20℃.
Shipping Conditions: RT
