Description
CYCS Polyclonal Antibody | E-AB-40209 | Gentaur US, UK & Europe Disrtribition
Reactivity: Human, Bovine
Host: Rabbit
Isotype: IgG
Application: WB, IHC
Research Area: Cancer, Cell Biology, Cardiovascular, Metabolism, Signal Transduction
Background: Cytochrome c is a 12-15 kDa electron transporting protein located in the inner mitochondrial membrane. Upon apoptotic stimulation, cytochrome c can be released from mitochondria into cytoplasm, resulting in caspase-3 activation and apoptosis. Measurement of cytochrome c release from the mitochondria is useful for detection of the onset of apoptosis in cells. In addition, cytochrome c can also leave cells and be detectable in extra-cellular medium of apoptotic cells and serum of cancer patients. The level of serum cytochrome c may serve as a prognostic maker during cancer therapy.
Lead Time: 7~10 days
Concentration: 2 mg/mL
Storage: Store at -20°C. Avoid freeze / thaw cycles.
Immunogen: Recombinant Human Cytochrome c protein
Buffer: PBS with 0.05% Proclin300 and 50% glycerol, pH7.4.
Purification: Affinity purification
Dilution: WB 1:1000-1:2000 IHC 1:100-1:200
Conjugation: Unconjugated
Calculated Molecular Weight: 12 kDa
Observed Molecular Weight: 12 kDa
Clonality: Polyclonal
