CYCS Polyclonal Antibody | E-AB-40209

CYCS Polyclonal Antibody | E-AB-40209 | Gentaur US, UK & Europe Disrtribition

Reactivity: Human, Bovine

Host: Rabbit

Isotype: IgG

Application: WB, IHC

Research Area: Cancer, Cell Biology, Cardiovascular, Metabolism, Signal Transduction

Background: Cytochrome c is a 12-15 kDa electron transporting protein located in the inner mitochondrial membrane. Upon apoptotic stimulation, cytochrome c can be released from mitochondria into cytoplasm, resulting in caspase-3 activation and apoptosis. Measurement of cytochrome c release from the mitochondria is useful for detection of the onset of apoptosis in cells. In addition, cytochrome c can also leave cells and be detectable in extra-cellular medium of apoptotic cells and serum of cancer patients. The level of serum cytochrome c may serve as a prognostic maker during cancer therapy.

Lead Time: 7~10 days

Concentration: 2 mg/mL

Storage: Store at -20°C. Avoid freeze / thaw cycles.

Immunogen: Recombinant Human Cytochrome c protein

Buffer: PBS with 0.05% Proclin300 and 50% glycerol, pH7.4.

Purification: Affinity purification

Dilution: WB 1:1000-1:2000 IHC 1:100-1:200

Conjugation: Unconjugated

Calculated Molecular Weight: 12 kDa

Observed Molecular Weight: 12 kDa

Clonality: Polyclonal