Cyclin D1 Antibody / CCND1 | V9073-20UG

Cyclin D1 Antibody / CCND1 | V9073-20UG | Gentaur US, UK & Europe Disrtribition

Family: Primary antibody

Formulation: 0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced) and 0.05% sodium azide

Format: Purified

Clone: SPM587

Host Animal: Mouse

Clonality: Monoclonal (mouse origin)

Species Reactivity: Human, Mouse

Application: WB, IHC-P, FACS

Buffer: N/A

Limitation: This CCND1 antibody is available for research use only.

Purity: Protein G affinity chromatography

Description: Cyclin D1 (CCND1), one of the key cell cycle regulators, is a putative proto-oncogene overexpressed in a wide variety of human neoplasms. About 60% of mantle cell lymphomas (MCL) contain a t(11; 14)(q13; q32) translocation resulting in over-expression of Cyclin D1. This antibody is useful in identifying mantle cell lymphomas (CCND1+) from CLL/SLL and follicular lymphomas (CCND1-). Occasionally, hairy cell leukemia and plasma cell myeloma weakly express CCND1.

Immunogen: Recombinant full length human protein was used as the immunogen for this CCND1 antibody.

Storage: Store the CCND1 antibody at 2-8oC (with azide) or aliquot and store at -20 °C or colder (without azide).