Description
Cyclin B1 Antibody | R31529 | Gentaur US, UK & Europe Disrtribition
Family: Primary antibody
Formulation: 0.5mg/ml if reconstituted with 0.2ml sterile DI water
Format: Antigen affinity purified
Clone: N/A
Host Animal: Rabbit
Clonality: Polyclonal (rabbit origin)
Species Reactivity: Human
Application: WB, IF, FACS
Buffer: N/A
Limitation: This Cyclin B1 antibody is available for research use only.
Purity: Antigen affinity
Description: Cyclin B1 is a protein that in humans is encoded by the CCNB1 gene, and it is mapped to 5q13.2. It is a regulatory protein involved in mitosis. The gene product complexes withp34(Cdc2)to form the maturation-promoting factor (MPF). Two alternative transcripts have been found, a constitutively expressed transcript and a cell cycle-regulated transcript, that is expressed predominantly during G2/M phase. The different transcripts result from the use of alternate transcription initiation sites. CCNB1 contributes to the switch-like all or none behavior of the cell in deciding to commit to mitosis. Its activation is well-regulated, and positive feedback loops ensure that once theCyclin B1-Cdk1complex is activated, it is not deactivated.
Immunogen: Human partial recombinant protein (AA 1-433) was used as the immunogen for this Cyclin B1 antibody.
Storage: After reconstitution, the Cyclin B1 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20 °C. Avoid repeated freezing and thawing.
