Cyclin A2(E67), CF488A conjugate, 0.1mg/mL Antibody | BNC880673-100

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SKU:
37-BNC880673-100
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Weight:
1.00 KGS
€418.00
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Description

Cyclin A2(E67), CF488A conjugate, 0.1mg/mL Antibody | BNC880673-100| Gentaur Distribution US, UK & Europe

Summary.: This antibody recognizes a protein of 54 kDa, which is identified as cyclin A. Its epitope is located in amino acids 144-148 of human Cyclin A2. Cyclins are regulatory subunits of the cyclin-dependent kinases (cdk's) and they control transition at different specific phases of the cell cycle. The temporal expression of cyclins is tightly regulated and subsequently plays a critical role in controlling the enzymatic activity of cdk's. These cyclin/cdk complexes are essential for passage through specific stages in the cell cycle. In mammalian somatic cells, cyclin A is required for S-phase and passage through G2-phase. The D and E type cyclins regulate the passage of G1, while cyclin B is a critical regulator of mitosis. Mutation or disruption of normal cyclin A expression causes cells to arrest in G2-phase. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors. .

Conjugate: CF488A.

Storage Buffer: PBS, 0.1% BSA, 0.05% azide.

Storage Temperature: 2°C to 8°C.

Application: IHC, FFPE (verified)|WB (verified).

Stability: Stable at room temperature or 37°C (98°F) for 7 days.

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Additional Information

Size:
100 uL
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