Description
CUX1 Antibody | F49389-0.08ML | Gentaur US, UK & Europe Disrtribition
Family: Primary antibody
Formulation: In 1X PBS, pH 7.4, with 0.09% sodium azide
Format: Antigen affinity purified
Clone: N/A
Host Animal: Rabbit
Clonality: Polyclonal (rabbit origin)
Species Reactivity: Human
Application: WB, IHC, IF, ELISA
Buffer: N/A
Limitation: This CUX1 antibody is available for research use only.
Purity: Antigen affinity
Description: CUX1 likely has a broad role in mammalian development as a repressor of developmentally regulated gene expression. May act by preventing binding of positively-activing CCAAT factors to promoters. Component of nf-munr repressor; binds to the matrix attachment regions (MARs) (5' and 3') of the immunoglobulin heavy chain enhancer. Represses T-cell receptor (TCR) beta enhancer function by binding to MARbeta, an ATC-rich DNA sequence located upstream of the TCR beta enhancer. Binds to the TH enhancer; may require the basic helix-loop-helix protein TCF4 as a coactivator (By similarity). [UniProt]
Immunogen: A portion of amino acids 1347-1374 from the human protein was used as the immunogen for this CUX1 antibody.
Storage: Aliquot the CUX1 antibody and store frozen at -20 °C or colder. Avoid repeated freeze-thaw cycles.
