CTSD Antibody / Cathepsin D | V7702SAF-100UG

CTSD Antibody / Cathepsin D | V7702SAF-100UG | Gentaur US, UK & Europe Disrtribition

Family: Primary antibody

Formulation: 1 mg/ml in 1X PBS; BSA free, sodium azide free

Format: Purified

Clone: CTSD/3082

Host Animal: Mouse

Clonality: Monoclonal (mouse origin)

Species Reactivity: Human

Application: IHC-P, WB

Buffer: N/A

Limitation: This Cathepsin D antibody is available for research use only.

Purity: Protein G affinity chromatography

Description: Cathepsin D is a ubiquitously expressed lysosomal aspartyl protease involved in the normal degradation of proteins. It is synthesized as an inactive 52kDa preprocathepsin D that is cleaved and glycosylated to form a 48kDa procathepsin D and then further cleaved to produce 34kDa and 14kDa subunits (heavy and light chains, respectively). Cathepsin D exhibits pepsin-like activity and plays a role in protein turnover and in the proteolytic activation of hormones and growth factors. Mutations in this gene play a causal role in neuronal ceroid lipofuscinosis-10 and may be involved in the pathogenesis of several other diseases, including breast cancer and possibly Alzheimer's disease.

Immunogen: A recombinant human partial protein (amino acids 104-250) was used as the immunogen of the Cathepsin D antibody.

Storage: Store the Cathepsin D antibody at 2-8oC (with azide) or aliquot and store at -20 °C or colder (without azide).