CTLA-4 Antibody / CD152 | RQ5483

CTLA-4 Antibody / CD152 | RQ5483 | Gentaur US, UK & Europe Disrtribition

Family: Primary antibody

Formulation: Antibody in PBS with 0.02% sodium azide and 50% glycerol

Format: Purified

Clone: ADCD-3

Host Animal: Rabbit

Clonality: Rabbit Monoclonal

Species Reactivity: Human, Mouse, Rat

Application: WB

Buffer: N/A

Limitation: This CD152 antibody is available for research use only.

Purity: Affinity purified

Description: The CTLA4 gene is a member of the immunoglobulin superfamily and encodes a protein which transmits an inhibitory signal to T cells. The protein contains a V domain, a transmembrane domain, and a cytoplasmic tail. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. The membrane-bound isoform functions as a homodimer interconnected by a disulfide bond, while the soluble isoform functions as a monomer. Mutations in this gene have been associated with insulin-dependent diabetes mellitus, Graves disease, Hashimoto thyroiditis, celiac disease, systemic lupus erythematosus, thyroid-associated orbitopathy, and other autoimmune diseases. [RefSeq]

Immunogen: A synthetic peptide specific to human CD152 / CTLA4 was used as the immunogen for the CD152 antibody.

Storage: Store the CD152 antibody at -20 °C.