CST6 Polyclonal Antibody | E-AB-14922

CST6 Polyclonal Antibody | E-AB-14922 | Gentaur US, UK & Europe Disrtribition

Reactivity: Human

Host: Rabbit

Isotype: IgG

Application: IHC, ELISA

Research Area: Cell Biology

Background: The cystatin superfamily encompasses proteins that contain multiple cystatin-like sequences. Some of the members are active cysteine protease inhibitors, while others have lost or perhaps never acquired this inhibitory activity. There are three inhibitory families in the superfamily, including the type 1 cystatins (stefins), type 2 cystatins and the kininogens. The type 2 cystatin proteins are a class of cysteine proteinase inhibitors found in a variety of human fluids and secretions, where they appear to provide protective functions. This gene encodes a cystatin from the type 2 family, which is down-regulated in metastatic breast tumor cells as compared to primary tumor cells. Loss of expression is likely associated with the progression of a primary tumor to a metastatic phenotype.

Lead Time: 7~10 days

Concentration: 0.7 mg/mL

Storage: Store at -20°C. Avoid freeze / thaw cycles.

Immunogen: Recombinant protein of human CST6

Buffer: PBS with 0.05% sodium azide and 50% glycerol, PH7.4

Purification: Affinity purification

Dilution: IHC 1:100-1:300

Conjugation: Unconjugated

Calculated Molecular Weight: N/A

Observed Molecular Weight: N/A

Clonality: Polyclonal