Description
CSK Antibody | R31527 | Gentaur US, UK & Europe Disrtribition
Family: Primary antibody
Formulation: 0.5mg/ml if reconstituted with 0.2ml sterile DI water
Format: Antigen affinity purified
Clone: N/A
Host Animal: Rabbit
Clonality: Polyclonal (rabbit origin)
Species Reactivity: Human, Mouse, Rat
Application: WB, IHC-P
Buffer: N/A
Limitation: This CSK antibody is available for research use only.
Purity: Antigen affinity
Description: CSK is a non-receptor protein tyrosine kinase protein that in humans is encoded by the CSK gene. It is mapped to 15q24.1. CSK suppresses activity of the Src family of protein kinases by phosphorylation of family members at a conserved C-terminal site in Src. CSKs control of the Src family activity is widely thought to be central to regulation of the immune response. It can downregulate tyrosine kinase activity of the Src oncoprotein through tyrosine phosphorylation of the carboxy terminus. Since cell transformation by Src oncoproteins is caused by various mechanisms that interfere with this phosphorylation, the gene might function as an antioncogene.
Immunogen: Human partial recombinant protein (AA 2-204) was used as the immunogen for this CSK antibody.
Storage: After reconstitution, the CSK antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20 °C. Avoid repeated freezing and thawing.
