Description
Crystallin-alpha C Monoclonal Antibody | E-AB-22177 | Gentaur US, UK & Europe Disrtribition
Reactivity: Human, Mouse, Rat
Host: Mouse
Isotype: IgG
Application: WB
Research Area: Cancer, Neuroscience, Signal Transduction
Background: The protein encoded by this gene belongs to the superfamily of small heat-shock proteins containing a conservative alpha-crystallin domain at the C-terminal part of the molecule. The expression of this gene in induced by estrogen in estrogen receptor-positive breast cancer cells, and this protein also functions as a chaperone in association with Bag3, a stimulator of macroautophagy. Thus, this gene appears to be involved in regulation of cell proliferation, apoptosis, and carcinogenesis, and mutations in this gene have been associated with different neuromuscular diseases, including Charcot-Marie-Tooth disease.
Lead Time: 7~10 days
Concentration: 1 mg/mL
Storage: Store at -20°C. Avoid freeze / thaw cycles.
Immunogen: Recombinant Protein
Buffer: PBS with 0.02% sodium azide, 0.5% BSA and 50% glycerol, pH7.4
Purification: Protein A purification
Dilution: WB 1:1000-2000
Conjugation: Unconjugated
Calculated Molecular Weight: N/A
Observed Molecular Weight: 22 kDa
Clonality: Monoclonal
