Description
CRK Antibody (phospho-S41) | F40128-0.08ML | Gentaur US, UK & Europe Disrtribition
Family: Primary antibody
Formulation: In 1X PBS pH 7.4 with 0.09% sodium azide
Format: Antigen affinity purified
Clone: N/A
Host Animal: Rabbit
Clonality: Polyclonal (rabbit origin)
Species Reactivity: Human
Application: DB, ELISA
Buffer: N/A
Limitation: This phospho-CRK antibody is available for research use only.
Purity: Antigen affinity
Description: CRK is a member of an adapter protein family that binds to several tyrosine-phosphorylated proteins. It has several SH2 and SH3 domains (src-homology domains) and is involved in several signaling pathways, recruiting cytoplasmic proteins in the vicinity of tyrosine kinase through SH2-phosphotyrosine interaction. The N-terminal SH2 domain of this protein functions as a positive regulator of transformation whereas the C-terminal SH3 domain functions as a negative regulator of transformation.
Immunogen: This phospho-CRK antibody was produced from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding pS41 of human CRK.
Storage: Aliquot the phospho-CRK antibody and store frozen at -20 °C or colder. Avoid repeated freeze-thaw cycles.
