Description
COX-2 Monoclonal Antibody | PA6678 | Gentaur US, UK & Europe Disrtribition
Clone : YN00556m
Reactivity : Human
Application : IHC-P
Host : Mouse
Category : RTU for IHC
Concentration : 100μg/mL for the RTU antibody, 1mg/mL for the concentrated antibody
Buffer : TBS with 0.1% Proclin300, PH7.4
Backgound : Cox-2 is an inducible enzyme which can be involved in the cell reactions of growth factors, tumor promoters and cytokines, all of those factors can induce cox-2 overexpression. Cox-2 is also involved in the synthesis of prostaglandins. Cox-2 expression is significantly increased in 85-90% in colorectal adenocarcinoma patients, while cox-1 expression is unchanged.
