Cortactin Antibody | F53608-0.1ML

Cortactin Antibody | F53608-0.1ML | Gentaur US, UK & Europe Disrtribition

Family: Primary antibody

Formulation: In ascites with 0.09% sodium azide

Format: Ascites

Clone: 401CT8.6.3

Host Animal: Mouse

Clonality: Monoclonal (mouse origin)

Species Reactivity: Human

Application: WB, ELISA

Buffer: N/A

Limitation: This Cortactin antibody is available for research use only.

Purity: Ascites

Description: This gene is overexpressed in breast cancer and squamous cell carcinomas of the head and neck. The encoded protein is localized in the cytoplasm and in areas of the cell-substratum contacts. This gene has two roles: (1) regulating the interactions between components of adherens-type junctions and (2) organizing the cytoskeleton and cell adhesion structures of epithelia and carcinoma cells. During apoptosis, the encoded protein is degraded in a caspase-dependent manner. The aberrant regulation of this gene contributes to tumor cell invasion and metastasis. Three splice variants that encode different isoforms have been identified for this gene.

Immunogen: Purified His-tagged Cortactin protein fragment was used to produced this monoclonal Cortactin antibody.

Storage: Aliquot the Cortactin antibody and store frozen at -20 °C or colder. Avoid repeated freeze-thaw cycles.