Description
Cortactin Antibody | F53608-0.1ML | Gentaur US, UK & Europe Disrtribition
Family: Primary antibody
Formulation: In ascites with 0.09% sodium azide
Format: Ascites
Clone: 401CT8.6.3
Host Animal: Mouse
Clonality: Monoclonal (mouse origin)
Species Reactivity: Human
Application: WB, ELISA
Buffer: N/A
Limitation: This Cortactin antibody is available for research use only.
Purity: Ascites
Description: This gene is overexpressed in breast cancer and squamous cell carcinomas of the head and neck. The encoded protein is localized in the cytoplasm and in areas of the cell-substratum contacts. This gene has two roles: (1) regulating the interactions between components of adherens-type junctions and (2) organizing the cytoskeleton and cell adhesion structures of epithelia and carcinoma cells. During apoptosis, the encoded protein is degraded in a caspase-dependent manner. The aberrant regulation of this gene contributes to tumor cell invasion and metastasis. Three splice variants that encode different isoforms have been identified for this gene.
Immunogen: Purified His-tagged Cortactin protein fragment was used to produced this monoclonal Cortactin antibody.
Storage: Aliquot the Cortactin antibody and store frozen at -20 °C or colder. Avoid repeated freeze-thaw cycles.
